SPECTRAL CLUSTERING OF MULTIDIMENSIONAL GENETIC DATA

TitleSPECTRAL CLUSTERING OF MULTIDIMENSIONAL GENETIC DATA
Publication TypeJournal Article
Year of Publication2017
AuthorsZaevski T, Kounchev O, Palejev D, Stoimenova E
JournalAnnuaire de l’Université de Sofia “St. Kliment Ohridski”. Faculté de Mathématiques et Informatique
Volume104
Pagination201-215
ISSN0205-0808
Keywordsmultidimensional data analysis, RNA-Seq data analysis, spectral clustering
Abstract
The main purpose of the present paper is to initiate the application of methods from Spectral graph theory to the analysis of multidimensional genetic data, and in particular to the problem of detecting differential expression based on RNA-Seq data. Here we introduce a new algorithm, that is based on the method of Spectral Clustering and integrates an additional information about a priori given relations among the genes.
2010 MSC

62-07, 62H30, 91C20, 92D20

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